- Palo Alto Networks has acquired Portkey to strengthen the Prisma AIRS AI security platform
- The Portkey technology will provide centralized governance and control for enterprise AI interactions
- The deal advances Palo Alto Networks’ strategy to secure autonomous AI agents and production-scale deployments
Palo Alto Networks has completed its acquisition of AI gateway provider Portkey, expanding the capabilities of the Prisma AIRS artificial intelligence security platform as organizations increase adoption of autonomous AI agents.
Portkey’s technology will serve as the foundational AI gateway within Prisma AIRS, providing a centralized control plane to monitor, orchestrate and govern AI interactions across enterprise environments, Palo Alto Networks said May 29.
The company noted the integration is intended to help organizations address emerging security, governance and cost-management challenges associated with agentic AI systems that can independently execute tasks and interact with enterprise applications.
How Will Portkey Enhance Prisma AIRS?
Portkey’s AI gateway architecture is designed to process large-scale AI workloads and can be deployed with minimal implementation effort.
As part of Prisma AIRS, the technology will provide:
- Runtime inspection of AI traffic to identify and mitigate agent-based threats
- Agent identity authentication through Palo Alto Networks’ Idira technology to help prevent unauthorized tool access and lateral movement
- AI observability capabilities through Chronosphere integration to monitor the performance and reliability of AI workloads
Lee Klarich, chief product and technology officer of Palo Alto Networks, said the company is combining internal development with acquisitions to keep pace with rapid advancements in AI technology.
“By making Portkey a critical component of the comprehensive Prisma AIRS platform, we do the heavy lifting of integration so our customers don’t have to, enabling them to adopt the latest AI capabilities with speed and security,” Klarich said.
According to Rohit Agarwal, Portkey’s CEO and co-founder, said the combination will help organizations move AI initiatives from pilot programs into production environments.
How Does the Acquisition Support Palo Alto Networks’ Agentic AI Strategy?
The transaction builds on the company’s March launch of Prisma AIRS 3.0, which introduced new capabilities designed to secure the full lifecycle of autonomous AI agents.
At the time, Palo Alto Networks unveiled an AI Agent Gateway in limited preview, describing it as a centralized platform for enforcing runtime security, identity controls, governance and observability for agentic AI deployments.
The company said Prisma AIRS 3.0 enables organizations to discover AI agents running in cloud, software-as-a-service and endpoint environments, and assess agent security risks through vulnerability scanning and red teaming.
What Other AI Security Acquisitions Has Palo Alto Networks Completed?
The Portkey acquisition is the latest in a series of moves by Palo Alto Networks to expand its AI and identity security portfolio.
In July 2025, the company finalized its acquisition of Protect AI, a company specializing in securing AI applications and models.
Earlier this year, Palo Alto Networks completed its $25 billion acquisition of identity security provider CyberArk. Palo Alto Networks said CyberArk’s privileged access management capabilities would be integrated into the Cortex and Strata platforms to help secure human, machine and AI agent identities.
